Current neuropharmacology

How Gut Bacteria and the Brain Interact in Mental Health Disorders: Causes and New Treatments

Updated

Abstract

Recent studies indicate that variations in the microbiome are associated with diverse neuropsychiatric disorders.

  • Neuropsychiatric disorders such as autism, depression, anxiety, and schizophrenia may be influenced by the gut microbiome.
  • Microbial substrates, as well as exogenous prebiotics, antibiotics, and probiotics, could modulate these disorders.
  • The microbiota-gut-brain axis is proposed as a potential target for the prevention and treatment of neuropsychiatric disorders.
  • Further studies are needed to confirm the clinical efficacy of probiotics, prebiotics, and fecal microbiota transplantation (FMT).

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