Microbiome and nutrition in autism spectrum disorder: current knowledge and research needs

Nov 20, 2016Nutrition reviews

Gut bacteria and diet in autism: what we know and what still needs study

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Abstract

Autism spectrum disorder (ASD) is the fastest growing neurodevelopmental disorder in the United States.

  • Environmental factors may contribute to the rising diagnosis rates of ASD alongside genetic risks.
  • Abnormalities in gut bacteria composition and microbial metabolites have been observed in children with ASD.
  • Gastrointestinal discomfort, food selectivity, and picky eating patterns are commonly reported in children with ASD.
  • Mechanisms involving nutrition, gut bacteria, and ASD symptoms may operate through immune, hormonal, or neuronal pathways.
  • Current evidence regarding the gut environment and nutritional status of children with ASD is reviewed.
  • Future studies are needed to explore the relationship between diet and gut bacteria in children with ASD.

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