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The microbiota–gut–brain axis and its potential therapeutic role in autism spectrum disorder
The gut bacteria and brain connection and its possible treatment role in autism
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Abstract
Disruptions in the microbiota-gut-brain axis are associated with autistic behaviors in individuals with autism spectrum disorder (ASD).
- Autism spectrum disorder (ASD) is linked to deficits in social and cognitive functions.
- Gastrointestinal symptoms and changes in gut microbiota composition frequently occur alongside cerebral disorders in ASD patients.
- Disturbances in gut microbiota may result from bacterial infections or long-term antibiotic use.
- The microbiota-gut-brain axis operates through neuroendocrine, neuroimmune, and autonomic nervous systems.
- Probiotics, helminthes, and specific diets are suggested as potential treatments targeting the microbiota-gut-brain axis.
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