Neuroscience

The gut bacteria and brain connection and its possible treatment role in autism

Updated

Abstract

Disruptions in the microbiota-gut-brain axis are associated with autistic behaviors in individuals with autism spectrum disorder (ASD).

  • Autism spectrum disorder (ASD) is linked to deficits in social and cognitive functions.
  • Gastrointestinal symptoms and changes in gut microbiota composition frequently occur alongside cerebral disorders in ASD patients.
  • Disturbances in gut microbiota may result from bacterial infections or long-term antibiotic use.
  • The microbiota-gut-brain axis operates through neuroendocrine, neuroimmune, and autonomic nervous systems.
  • Probiotics, helminthes, and specific diets are suggested as potential treatments targeting the microbiota-gut-brain axis.

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