Autism Spectrum Disorder as a Brain-Gut-Microbiome Axis Disorder

Feb 15, 2020Digestive diseases and sciences

Autism as a Disorder Involving Interactions Between the Brain, Gut, and Microbes

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Abstract

Gastrointestinal issues significantly impact quality of life for individuals with autism spectrum disorder (ASD).

  • There is a relationship between the gut microbiome and gastrointestinal symptoms in individuals with ASD.
  • Behavioral symptoms may also be influenced by the gut microbiome.
  • Microbial therapies, such as probiotics and fecal microbiota transplantation, have shown potential in treating gastrointestinal symptoms associated with ASD.
  • Future research needs to focus on the complex variations within ASD for better study designs and therapeutic interventions.
  • Large, diverse studies with well-controlled designs are essential to advance understanding in this area.

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