International journal of molecular sciences

The Role of Gut Bacteria in Diagnosing and Treating Autism Spectrum Disorder

Updated

Abstract

Alterations in gut microbiota are highlighted in the context of autism spectrum disorder (ASD).

  • The gut microbiota may influence neurodevelopment through various signaling pathways.
  • Key pathways involved include the GABAergic system, serotonergic system, and mTOR signaling.
  • Microbiota-targeted strategies such as fecal microbiota transplantation (FMT), probiotics, and dietary approaches are evaluated for potential diagnosis and treatment.
  • The review critically appraises the role of the microbiota-gut-brain axis in ASD.

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Full Text

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Funding

Competing interests

The authors declare no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the decision to publish the results.
PubMed

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