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Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system
Gut bacteria interact with the brain through hormone-producing gut cells and the gut nervous system
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Abstract
The microbiota-gut-brain axis facilitates communication between the gut and the central nervous system.
- This communication links emotional and cognitive functions of the brain with gut processes.
- It involves various gut-derived peptides and amines produced by enteroendocrine cells.
- Neural networks, including the enteric and autonomic nervous systems, play a role in this communication.
- Research indicates the gut microbiota may influence normal physiology and contribute to disease.
- Understanding of this bidirectional communication system is still in the early stages.
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