Biomedical research (Tokyo, Japan)

Gut bacteria interact with the brain through hormone-producing gut cells and the gut nervous system

Updated

Abstract

The microbiota-gut-brain axis facilitates communication between the gut and the central nervous system.

  • This communication links emotional and cognitive functions of the brain with gut processes.
  • It involves various gut-derived peptides and amines produced by enteroendocrine cells.
  • Neural networks, including the enteric and autonomic nervous systems, play a role in this communication.
  • Research indicates the gut microbiota may influence normal physiology and contribute to disease.
  • Understanding of this bidirectional communication system is still in the early stages.

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