Journal of the American Society of Nephrology : JASN

Estimating Who Qualifies for Combined Heart and Kidney Treatment and How Many Deaths Could Be Prevented

Updated

Abstract

Clinical guidelines recommend the use of four specific drug classes to reduce cardiorenal risk.

  • Renin-angiotensin system inhibitors, sodium-glucose cotransporter-2 inhibitors, glucagon-like peptide-1 receptor agonists, and nonsteroidal mineralocorticoid receptor antagonists are suggested for combined use.
  • Eligibility criteria for combination treatment among patients is not well defined.
  • The potential impact of these combined treatments on mortality prevention is currently unclear.

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