Mirtazapine, an antidepressant

Mirtazapine is FDA-approved for treating depression and may also aid in anxiety management.

• Mirtazapine blocks specific receptors involved in neurotransmission, which may enhance its antidepressant effects.
• Patients taking mirtazapine demonstrated significantly greater improvement in depression symptoms compared to those on placebo, as measured by the Hamilton Rating Scale for Depression.
• It has shown comparable efficacy to other established antidepressants such as amitriptyline, clomipramine, and doxepin.
• Common adverse effects include somnolence, increased appetite, weight gain, and dizziness, but mirtazapine is generally well tolerated.
• The recommended starting dosage is 15 mg/day, taken as a single dose at bedtime.

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