Protocols for Mitochondria as the Target of Pharmacological Therapy in the Context of Nonalcoholic Fatty Liver Disease (NAFLD)

Jun 7, 2021Methods in molecular biology (Clifton, N.J.)

Treatment Approaches Targeting Mitochondria in Nonalcoholic Fatty Liver Disease

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Abstract

Mitochondrial dysfunction is involved in the progression of nonalcoholic fatty liver disease (NAFLD) to more severe liver conditions.

  • NAFLD is a prevalent chronic liver disease in developed countries that can lead to serious complications.
  • Liver mitochondria may be a key target for treatments aimed at enhancing liver function in NAFLD patients.
  • Current therapeutic options for NAFLD are discussed, based on both experimental and clinical evidence.
  • Novel strategies for improving mitochondrial function in NAFLD are presented.

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