Chronobiology internationalAug 13, 2019

Can Multidisciplinary Therapy Improve Day-to-Day Rhythm and Sleep Quality in Binge Eating Disorder?

Circadian Biology Weekly Brief ↗PubMed ↗DOI ↗

Updated Apr 2, 2026

Abstract

Women with Binge Eating Disorder (BED) exhibited significantly reduced levels of MESOR and Amplitude compared to a control group.

The actigraphic monitoring revealed differences in circadian rhythm metrics between the BED group and controls.
Interdaily stability, which is linked to sleep efficiency, was higher in the BED group, suggesting better synchronization of their rest-activity rhythm.
Sleep parameters did not show significant differences between the two groups in previous analyses.
The multidisciplinary therapy, which included cognitive-behavioral therapy and nutritional guidance, may contribute to improved lifestyle regularity.
A regular lifestyle is associated with the maintenance of a stable sleep-wake cycle in patients with eating disorders.

Simplified

We have recently shown that rest-activity circadian rhythm significantly differed in women with Binge Eating Disorder (BED) compared to the Ctrl group. In details, patients with BED exhibited significantly reduced levels of MESOR and Amplitude with respect to the Ctrl group. In addition, in this previous study, the results of the actigraphic sleep monitoring provided no evidence of differences in sleep parameters between the two groups. We expanded the original sample obtaining a total of 28 volunteered women, 14 BED women, and 14 Ctrl. We recorded in all 28 participants a 5-day actigraphic monitoring to detect the rhythmometric parameters, interdaily stability, intradaily variability, L5, M10, and sleep parameters. During the study, BED's women group kept an individual multidisciplinary therapy lasting five weekly days, from Monday to Friday, consisting in cognitive-behavioral therapy and nutritional program, administered in outpatient care from 8:00 a.m. at 5:00 p.m. The combination of both our previous and current study supports the conclusion that the sleep quality of the BED group is significantly better compared to Ctrl. The non-parametric indexes showed how interdaily stability, significantly correlated to sleep efficiency, was higher in BED group compared to the Ctrl group, indicating a better synchronization of rest-activity circadian rhythm. In conclusion, the maintenance of a regular lifestyle, such as imposed by the multidisciplinary therapy, is important to avoid alterations in the sleep-wake cycle, particularly in patients with eating disorders.

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Can Multidisciplinary Therapy Improve Day-to-Day Rhythm and Sleep Quality in Binge Eating Disorder?

Abstract

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