Muscle-targeted nanoparticle vaccines trigger strong immune responses against chickenpox virus

Declarations. Ethics approval and consent to participate: All cell lines were cultured in the conditions recommended by the manufacturers and collaborators, and only used for research purposes specifically described in this research article. All the animal experiments were kept to the National Regulation of China for Care and Use of Laboratory Animals. Both female BALB/c mice and female C57BL/6 mice were purchased from Beijing Huafukang Biotech Co., Ltd. (Beijing, China). The mice were housed in a ventilated, temperature-controlled, and illumination-controlled animal facility without specific pathogen (20 ± 2 °C; 50% ± 10%; illumination, 8:00–20:00; dark, 20:00–8:00). Consent to publish: All the authors read and approved the final version of the manuscript. Competing interests: All authors were employed by Beijing Youcare Kechuang Pharmaceutical Technology Co. Ltd. G.S. and H.Z. are inventors on a pending patent related to this work filed by Beijing Youcare Kechuang Pharmaceutical Technology Co. Ltd.