Clinical nutrition ESPEN

Natural Foods That May Influence Weight Control by Affecting a Key Hormone Receptor

Updated

Abstract

The glucagon-like peptide-1 receptor (GLP-1R) is a significant target in treating obesity and metabolic diseases.

  • GLP-1R plays a crucial role in regulating appetite, gastric emptying, insulin secretion, and energy balance.
  • Pharmacological GLP-1R agonists are associated with significant weight loss and improvements in blood sugar levels.
  • There is increasing interest in natural dietary components that may enhance the body's own GLP-1 signaling.

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