Among 716 adolescents with elevated depression and anxiety symptoms, restlessness and sad mood were identified as key factors related to .
'Sad mood' was found to be directly related to suicide ideation, showing the highest variance among symptoms.
The depression-anxiety symptom network differed significantly between adolescents with and without suicide ideation.
'Restlessness' and 'sad mood' had a greater influence in the symptom network for those experiencing suicide ideation.
Central symptoms in the network included 'restlessness', 'sad mood', and 'trouble relaxing'.
'Restlessness', 'nervousness', and 'reduced movement' were identified as bridge symptoms connecting depression and anxiety.
Simplified
BACKGROUND: The co-occurrence of depression and anxiety among adolescents is typically associated with .
AIMS: The study aimed to investigate the symptom-level relationship between suicide ideation and the comorbidity of depression and anxiety.
METHODS: 1501 adolescents aged 12-19 years were assessed using the Patient Health Questionnaire (PHQ-9) and the Generalized Anxiety Disorder Scale, and 716 adolescents who scored ≥5 on both scales were selected as participants. was used to identify the network structure of depressive symptoms and anxiety symptoms. Participants were categorised into either the suicide ideation or non-suicide ideation groups based on their scoring on the suicide-related item in PHQ-9. A comparison was made between the depression-anxiety symptom networks of the two groups.
RESULTS: 'Restlessness', 'sad mood' and 'trouble relaxing' were the most prominent central symptoms in the depression-anxiety symptom network, and 'restlessness', 'nervousness' and 'reduced movement' were the bridge symptoms in this network. 'Sad mood' was found to be directly related to 'suicide ideation' with the highest variance. The network structure was significantly different in properties between the suicide ideation group and the non-suicide ideation group, with 'restlessness' and 'sad mood' exhibiting significantly higher influence in the network of the suicide ideation group than that in the non-suicide ideation group.
CONCLUSION: Restlessness and sad mood could be targeted for the intervention of depression-anxiety symptoms among adolescents with suicide ideation.
Key numbers
409
Participants with
Out of 716 adolescents assessed for depression and anxiety symptoms.
307
Participants without
The remaining adolescents assessed for depression and anxiety symptoms.
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