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Ninjin'yoeito affects eating and activity during low energy by acting on the appetite control system
Updated
Abstract
Ninjin-yoeito (NYT) may enhance feeding and energy conservation through neuropeptide Y (NPY) pathways.
- The NPY system is crucial for regulating feeding and energy balance.
- Aging and disease can impair the functionality of the NPY system.
- NYT, a kampo medicine made of twelve herbs, is associated with treating anorexia and frailty.
- Under low energy conditions, NYT promotes feeding and decreases activity to save energy.
- The effects of NYT appear to involve NPY signaling, as indicated by changes when Y4 receptors or peptide YY (PYY) are absent.
- These findings suggest potential for combination therapies targeting the NPY system to address aging-related energy regulation.
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