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Evaluation of Nocturnal Symptoms in Chinese Parkinson’s Disease Patients Based on the PDSS-2 Scale: A Multicenter Cross-Sectional Study
Nighttime Symptoms in Chinese Parkinson's Patients Measured by the PDSS-2 Scale
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Abstract
Among 1,500 Chinese Parkinson's disease patients, 38.4% reported nocturnal symptoms.
- Nocturnal symptoms were more prevalent in patients older than 65 years, with 59.2% in this age group.
- Patients experiencing nocturnal symptoms had a higher total score on the Parkinson's disease questionnaire (PDQ-8), indicating poorer quality of life.
- Moderate and severe depression were more frequently reported in patients with nocturnal symptoms, suggesting a link between these conditions.
- Anxiety levels were also higher in patients with nocturnal symptoms, indicating potential co-occurrence.
- Longer disease duration and more advanced were independently associated with the presence of nocturnal symptoms.
- Factors such as education level, depression, disease course, Hoehn-Yahr stage, and nocturnal symptoms were found to be related to quality of life.
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Key numbers
576 of 1,500
Prevalence of Nocturnal Symptoms
Patients with nocturnal symptoms out of total participants.
32.64
Quality of Life Score
PDQ-8 total score in patients with nocturnal symptoms.
59.2%
Older Patients with Nocturnal Symptoms
Percentage of patients with nocturnal symptoms aged over 65.