Non arteritic ischemic optic neuropathy in a patient taking semaglutide: Is there a relation? A case report and a review of the literature

Apr 4, 2025European journal of ophthalmology

Sudden vision loss linked to semaglutide use: A patient case and review

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Abstract

A case of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) occurred in a diabetic patient taking Semaglutide.

  • Clinical trials of Semaglutide did not report a significant increase in the risk of NAION.
  • A recent retrospective cohort study suggested a possible association between NAION and GLP-1 receptor agonists.
  • The association between NAION and Semaglutide is a subject of ongoing debate with conflicting study results.
  • Clinicians and ophthalmologists should consider the potential association when evaluating the risk-benefit ratio for patients.

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