Noninvasive nanoparticle strategies for brain tumor targeting

Jul 31, 2017Nanomedicine : nanotechnology, biology, and medicine

Using noninvasive nanoparticles to target brain tumors

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Abstract

Non-invasive nanoparticles may effectively deliver drugs to brain tumors by crossing the blood-brain barrier.

  • The blood-brain barrier is a significant obstacle for drug delivery to the central nervous system.
  • Recent advances in liposomes, polymeric nanoparticles, micelles, and inorganic nanoparticles are explored.
  • Effective drug delivery strategies could involve engineering nanoparticles with suitable sizes and surface characteristics.
  • The review emphasizes the importance of specific ligands in enhancing the ability of nanoparticles to cross the barrier.

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