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Abstract
Glucagon-like peptide-1 (GLP-1) receptor agonists may improve symptoms of hidradenitis suppurativa (HS).
- Hidradenitis suppurativa is characterized by painful and draining nodules in skin folds.
- There is a notable association between obesity and an increased prevalence of HS.
- Weight loss has been linked to symptom improvement in HS, but results from different methods vary.
- GLP-1 receptor agonists are effective for weight loss and have minimal significant side effects.
- Early studies suggest that liraglutide and semaglutide may reduce HS severity and enhance quality of life.
- Potential mechanisms for symptom improvement include reduced mechanical stress and decreased inflammation.
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