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Current and future use of incretin-based treatments for obesity and type 2 diabetes

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Abstract

The increasing rates of type 2 diabetes mellitus (T2DM) and obesity are driving the search for more effective therapeutic methods.

  • Current treatment options include monoagonists such as liraglutide, dulaglutide, and semaglutide.
  • Dual incretin receptor agonists like tirzepatide are also being explored for their potential benefits.
  • New classes of triple- and tetra-agonists of gastrointestinal hormones are under development.
  • These advancements may lead to more effective complex treatments for both T2DM and obesity.

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