Correlations between objective and subjective sleep and circadian markers in remitted patients with bipolar disorder

Mar 15, 2014Chronobiology international

Links between measured and reported sleep and body clock patterns in recovered bipolar disorder patients

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Abstract

Phase preference assessed by the Composite Scale of Morningness (CSM) strongly correlated with actigraphic phase markers (M10 onset ρ = -0.69 and L5 onset ρ = -0.63).

  • Twenty-six bipolar disorder patients in remission completed three sleep and circadian questionnaires and wore an actigraph for 21 days.
  • Sleep duration and sleep latency measured by the Pittsburgh Sleep Quality Index (PSQI) and actigraphy were highly correlated (ρ = -0.76; ρ = 0.50).
  • Moderate correlation coefficients were found between questionnaires and actigraphy for rhythm stability, sleep quality, sleep latency, and sleep disturbances (|ρ| > 0.40), though not significant after correction for multiple testing.
  • No correlation was observed for markers of rhythm amplitude.
  • The study supported the external validity of the CSM and PSQI for assessing phase preference, sleep duration, and latency.

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