Medicine

Improving sleep apnea does not reduce left heart enlargement in obese people during a weight loss program

Updated

Abstract

Participants with obesity and obstructive sleep apnea had a larger left atrial area (22.4 ± 5.6 cm²) compared to those without obstructive sleep apnea (18.8 ± 3.8 cm²; P = .008).

  • Obstructive sleep apnea (OSA) is associated with increased left atrial () area in individuals with severe obesity.
  • Average weight reduction after 12 months was 19.0 ± 15.7 kg among participants.
  • A significant decrease in the AHI of -12 ± 14) was observed in participants with OSA after weight reduction.
  • Despite improvements in OSA following weight loss, the left atrial area did not significantly decrease.
  • No significant associations were found between changes in AHI or body mass index and changes in left atrial area.

Simplified

Key numbers

22.4 ± 5.6 cm² vs 18.8 ± 3.8 cm²
Area Comparison
area in participants with OSA vs. without OSA at baseline.
68% of individuals with OSA
Weight Reduction Success Rate
Percentage of individuals with OSA achieving successful weight reduction.
-12 ± 14
Change in
Change in after one year in individuals with OSA.

Full Text

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