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Improvement of obstructive sleep apnea does not rescue left atrial enlargement in obese participants of a multimodal weight reduction program
Improving sleep apnea does not reduce left heart enlargement in obese people during a weight loss program
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Abstract
Participants with obesity and obstructive sleep apnea had a larger left atrial area (22.4 Β± 5.6 cmΒ²) compared to those without obstructive sleep apnea (18.8 Β± 3.8 cmΒ²; P = .008).
- Obstructive sleep apnea (OSA) is associated with increased left atrial () area in individuals with severe obesity.
- Average weight reduction after 12 months was 19.0 Β± 15.7 kg among participants.
- A significant decrease in the (ΞAHI of -12 Β± 14) was observed in participants with OSA after weight reduction.
- Despite improvements in OSA following weight loss, the left atrial area did not significantly decrease.
- No significant associations were found between changes in AHI or body mass index and changes in left atrial area.
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Key numbers
22.4 Β± 5.6 cmΒ² vs 18.8 Β± 3.8 cmΒ²
Area Comparison
area in participants with OSA vs. without OSA at baseline.
68% of individuals with OSA
Weight Reduction Success Rate
Percentage of individuals with OSA achieving successful weight reduction.
-12 Β± 14
Change in
Change in after one year in individuals with OSA.