The lancet. Diabetes & endocrinology

Long-term safety of oral orforglipron in Japanese people with type 2 diabetes

Updated

Abstract

Orforglipron, an oral GLP-1 receptor agonist, requires further evaluation in East Asian populations with type 2 diabetes.

  • The study focused on Japanese participants with type 2 diabetes.
  • Orforglipron may serve as an additional treatment alongside diet and exercise or oral diabetes medications.
  • Distinct pathophysiological characteristics in East Asian populations could influence treatment outcomes.

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