Journal of endocrinological investigation

Managing GLP-1 receptor drugs around surgery with special notes for brain surgery patients

Updated

Abstract

The use of glucagon-like peptide-1 receptor agonists (GLP-1RAs) is increasing among patients undergoing surgical procedures.

  • GLP-1RAs are associated with delayed gastric emptying, which may lead to residual gastric contents during surgery.
  • Patients undergoing cranial or spinal surgeries while on GLP-1RAs may experience increased risks of postoperative complications.
  • Common postoperative complications for these patients include aspiration, delayed extubation, and nausea and vomiting.
  • There is a need for focused clinical reviews to address the implications of GLP-1RA use in surgical settings.

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