We canβt show the full text here under this license. Use the link below to read it at the source.
Effect of perioperative intranasal insulin on postoperative delirium in elderly hip fracture patients undergoing general anesthesia: a randomized controlled study
Intranasal insulin during surgery and its link to delirium after hip fracture in elderly patients under general anesthesia
AI simplified
Abstract
The incidence of (POD) was 10.9% in elderly patients receiving compared to 30.4% in the control group.
- Postoperative delirium occurred in 20.7% of the overall study population.
- Intranasal insulin administration was associated with a significant reduction in POD incidence within five days post-surgery.
- On postoperative day 3, the insulin group showed a reduced POD incidence of 2.2%, compared to 19.6% in the control group.
- Serum levels of interleukin-6 and C-reactive protein were significantly lower in the insulin group compared to controls on postoperative day 1.
- Both groups experienced significant increases in interleukin-6 and C-reactive protein levels from baseline to postoperative day 1.
AI simplified
Key numbers
10.9%
Decrease in Incidence
incidence in the insulin group within five postoperative days.
2.2%
Incidence at Day 3
incidence in the insulin group on postoperative day 3.
20.7%
Overall Incidence
Total incidence across both groups during the study.