Revista espanola de medicina nuclear e imagen molecularAug 29, 2026

Ongoing tissue changes linked to fibroblasts in long COVID after moderate to severe initial illness

Updated Aug 30, 2026

Abstract

Fibroblast activation protein (FAP) may be visualized in patients with Long COVID using [⁶⁸Ga]Ga-FAPI PET/CT.

Persistent symptoms characterize Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC).
Fibroblast activation protein (FAP) is associated with activated fibroblasts during tissue remodeling.
Lung and muscle fibroblastic activity was investigated in patients who experienced moderate-to-severe COVID-19 pneumonia over two years after the acute infection.

Simplified

Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), is characterized by persistent symptoms. Fibroblast activation protein (FAP), expressed on activated fibroblasts during tissue remodeling, can be visualized with [⁶⁸Ga]Ga-FAPI PET/CT. This study investigated lung and muscle fibroblastic activity in patients with post-acute sequelae of COVID-19 (PASC) following moderate-to-severe COVID-19 pneumonia more than two years after the acute infection, using [⁶⁸Ga]Ga-FAPI PET/CT.

Full Text

Full text is available at the source.

View Full Text ↗

Ongoing tissue changes linked to fibroblasts in long COVID after moderate to severe initial illness

Abstract

Full Text

You found one interesting study. We’ll send the next 7.

What Lands in Your Inbox Each Week:

Recent issues from the long covid brief