British journal of clinical pharmacology

How a slow-release psilocybin is processed and tolerated in normal-weight and overweight adults

Updated

Abstract

The safety and tolerability of a novel oral modified-release psilocybin formulation (REL-P11) were evaluated in healthy adults.

  • The study included both normal-weight and overweight/obese participants.
  • Pharmacokinetics were assessed to understand how the body processes the new formulation.
  • The formulation aims for controlled, subperceptual exposure to psilocybin.
  • Emerging evidence suggests that serotonergic modulation could play a role in metabolic disorders.

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