Phase-advance shifts of human circadian pacemaker are accelerated by daytime physical exercise

Jun 19, 2001American journal of physiology. Regulatory, integrative and comparative physiology

Daytime exercise speeds up shifts in the human internal body clock

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Abstract

Plasma melatonin rhythm was significantly phase advanced with physical exercise during a 15-day forced sleep-wake schedule.

  • The study involved subjects adhering to a forced sleep-wake schedule of 23 hours and 40 minutes over 12 cycles.
  • Physical exercise was imposed twice per waking period for 2 hours each, using bicycle- or rowing-type ergometers.
  • After 6 days of exercise, a significant phase advancement in melatonin rhythm was observed.
  • The amplitude of the melatonin rhythm remained unchanged regardless of exercise.
  • Exercise in the afternoon or at midnight caused a significant phase delay in melatonin rhythms compared to the prepulse phase.
  • Phase shifts from exercise were not different from those observed in sedentary controls.

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