Phytochemical components of Hunteria umbellata (K. Schum) and its effect on isolated non-pregnant rat uterus in oestrus.

The aqueous extract of Hunteria umbellata demonstrated a significant uterine contractility effect at a concentration of 10 mg/ml.

• Phytochemical analysis of Hunteria umbellata revealed the presence of saponins, glycosides, steroids, tannins, volatile oils, phenols, and alkaloids.
• In vitro tests indicated that the extract's effect on uterine contractility was dose-dependent.
• The uterine contraction response to the extract was significantly affected (P<0.05) when compared to control.
• The presence of atropine blocked the effects of the extract, suggesting a specific mechanism of action.
• The extract enhanced the uterine response to oxytocin, supporting its traditional use to induce labor.

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