Polydatin helps balance energy production timing by controlling BMAL1 to prevent and treat fatty liver disease linked to metabolism problems

Polygonum cuspidatum is linked to conditions that may be associated with dyslipidemia, inflammation, and microcirculatory issues.

• Polygonum cuspidatum is traditionally used for disorders related to 'blood stasis' and 'damp-heat'.
• Its primary component, polydatin (PD), shows various biological activities.
• The specific impact of polydatin on metabolic dysfunction-associated fatty liver disease (MAFLD) is not yet understood.

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