Poor recovery sleep after sleep loss in people with delayed sleep phase syndrome

Sleep propensity curves showed clear differences between three patients with delayed sleep phase syndrome (DSPS) and seven healthy controls.

• DSPS patients did not recover sleep during the subjective day after sleep deprivation, unlike healthy controls.
• Melatonin production was absent during the subjective day for both groups.
• The findings suggest potential issues with sleep regulation mechanisms in DSPS patients following sleep deprivation.
• Differences in sleep patterns indicate that DSPS may be linked to disturbances in homeostatic sleep regulation.

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