Rapid detection of porcine reproductive and respiratory syndrome virus by reverse transcription loop-mediated isothermal amplification assay

Oct 18, 2008Journal of virological methods

Fast detection of pig reproductive and respiratory virus using a simple RNA amplification test

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Abstract

The RT-LAMP assay demonstrated a 91.3% sensitivity in detecting porcine reproductive and respiratory syndrome virus (PRRSV) in clinical samples.

  • The assay effectively detected all 22 different PRRSV isolates tested.
  • There was no cross-reaction with four other swine viruses: PCV2, SIV, CSFV, and PEDV.
  • Results were analyzed using agarose gel electrophoresis or a colorimetric method.
  • The assay can be performed in less equipped laboratories and field settings.

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