medRxiv : the preprint server for health sciencesOct 25, 2026

Care Patterns After Starting Semaglutide or Tirzepatide and Their Links to Weight Loss in Obesity Treatment

GLP-1 Therapies Weekly Brief ↗PubMed ↗DOI ↗OA ↗

Updated Oct 26, 2026

Abstract

Randomized trials indicate substantial weight loss with semaglutide and tirzepatide.

There is limited knowledge about the continuation of therapy in routine practice.
It is unclear if patients reach the maintenance dose of these medications.
Weight measurement practices for patients using these treatments are not well documented.

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