The Journal of clinical endocrinology and metabolism

Incretin treatment before pregnancy may lower pregnancy problems and heart-related risks in polycystic ovary syndrome

Updated

Abstract

Polycystic ovary syndrome (PCOS), also referred to as polyendocrine metabolic ovarian syndrome (PMOS), is associated with reproductive and cardiometabolic complications.

  • PCOS is linked to challenges in reproduction and heart-related health issues.
  • Glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP) receptor agonists may enhance outcomes related to obesity.
  • The effects of GLP-1 and GIP receptor agonists on pregnancy outcomes in individuals with PMOS are not yet clear.

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