Precooling (PC) before exercise may help prevent severe hyperthermia and exertional heatstroke (EHS). Before clinicians can advocate PC as an EHS prevention strategy, it must effectively mitigate factors associated with EHS development while not lessening the effectiveness of EHS treatment. Therefore, this study determined if PC affected rectal temperature (T), body heat storage, heart rate (HR), ratings of perceived exertion (RPE), thermal sensation, sweat rate, and postexercise cold-water immersion (CWI) Tcooling rates.In this randomized, crossover, counterbalanced study, 12 subjects (6 men, 6 women; age = 22 ± 2 yr; mass = 73.5 ± 7.9 kg; height = 171 ± 7 cm) underwent 15 min of CWI (10.0 ± 0.03°C) in an environmental chamber (38.6 ± 0.6°C; 36 ± 2% humidity). After a 10-min rest, they exercised to a Tof 39.5°C. Subsequently, they underwent CWI (9.99 ± 0.03°C) until Treached 38°C. On control (CON) days, the same procedures occurred without the 15-min PC intervention. T, HR, thermal sensation, and RPE were measured at various times before, during, and after exercise.PC lowered body heat storage and Tby 15.7 ± 15.0 W · mand 0.42 ± 0.40°C, respectively, before exercise. Subjects exercised significantly longer (PC = 66.7 ± 16.3 min, CON = 45.7 ± 9.5 min) and at lower T(∼0.5 ± 0.5°C) and HR (∼10 ± 7 bpm) following PC. PC significantly lowered sweat rate (PC = 1.02 ± 0.31 L · h, CON = 1.22 ± 0.39 L · h), but did not affect RPE or CWI cooling rates (PC = 0.18 ± 0.14°C · min; CON = 0.19 ± 0.05°C · min). Thermal sensation significantly differed between conditions only at pre-exercise (PC = 3 ± 1, CON = 5 ± 0.5).PC delayed severe hyperthermia and mitigated dehydration without affecting thermal perception or cooling rates posthyperthermia. PC may help prevent dangerous hyperthermia in athletes. BACKGROUND: METHODS: RESULTS: DISCUSSION: Wohlfert TM, Miller KC.. Aerosp Med Hum Perform. 2019; 90(1):12-17. Precooling, exertional heatstroke risk factors, and postexercise cooling rates rec rec rec rec rec rec rec -2 -1 -1 -1 -1
