Obesity science & practice

Preventing Weight Gain After Stopping Glucagon-Like Peptide-1 Treatment: A Small Randomized Trial

Updated

Abstract

A pilot randomized trial explored weight maintenance strategies after discontinuing glucagon-like peptide-1 receptor agonists (GLP-1 RAs).

  • Weight regain is common after stopping GLP-1 RAs, often occurring rapidly.
  • Few evidence-based strategies exist to support weight maintenance during this transition.
  • The trial investigated the effectiveness of a digital wellness application and medically tailored meals (MTM).
  • The focus was on the first 4 months following GLP-1 cessation.

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