Impact of protein coingestion on muscle protein synthesis during continuous endurance type exercise

Protein coingestion with carbohydrates increased whole body protein synthesis rates by 22 ± 3% during endurance exercise.

• Whole body protein oxidation rates increased by 70 ± 17% with protein coingestion during exercise.
• Whole body protein breakdown rates remained unchanged between carbohydrate-only and carbohydrate plus protein treatments.
• Net protein balance was slightly negative with carbohydrate alone and positive with carbohydrate plus protein treatment.
• Mixed muscle protein synthesis rates were higher during exercise compared to rest, but did not differ significantly between treatments.

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