PloS one

Testing the safety and potential benefits of psilocybin for treating anorexia in teens and young adults

Updated

Abstract

Anorexia nervosa (AN) is associated with high morbidity, mortality, and relapse rates, particularly in adolescents.

  • AN frequently emerges during adolescence, which may impact treatment outcomes.
  • Current psychological and nutritional treatments for AN result in suboptimal outcomes.
  • High rates of relapse and chronicity are observed in individuals with AN.
  • Preliminary evidence suggests psilocybin may have efficacy in treating psychiatric conditions characterized by rigidity.
  • Clinical evidence for the use of psilocybin in adolescents with AN is currently limited.

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