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Psychedelic 5-HT2A activator increases natural and triggered 5-Hz brain waves in vision and memory-related areas
Updated
Abstract
Essence
A psychedelic 5-HT2A agonist amplified spontaneous and visually evoked 5-Hz cortical rhythms in awake mice.
Evidence
Preclinical cortex-wide voltage-imaging experiments measured visual and retrosplenial cortex population activity in awake mice before and after 5-HT2A agonist injection.
Caveat
The abstract reports neural oscillation changes, not direct perceptual or hallucination outcomes, so the top-down-control mechanism remains inferred.
Simplified
Psychedelic Science