ACS medicinal chemistry letters

Developing improved psychedelic treatments by targeting serotonin and controlling drug timing

Updated

Abstract

Recent patents reveal new psychedelic compounds optimized for safer and shorter effects.

  • These compounds may enhance 5-HTA receptor modulation.
  • They could have fewer side effects compared to traditional psychedelics.
  • The duration of action may be adjustable to fit clinical needs.
  • Refinements involve modifying DMT and psilocin structures through prodrug design and fluorination.
  • These advancements aim to improve treatment predictability for psychiatric disorders.

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