How symptoms and medications affect sleep patterns in young people with anxiety, depression, and bipolar disorder

Among 146 youths with anxiety, depression, or bipolar disorders, mania symptoms were predictive of lower circadian amplitude and rhythmicity.

• Mania symptoms may independently affect the sleep-wake cycle, regardless of medication use.
• Antipsychotic medications are associated with longer sleep periods and duration.
• Serotonin-norepinephrine reuptake inhibitors may lead to longer sleep periods.
• Agomelatine is linked to earlier sleep onset.
• Different subclasses of psychotropic medications could have distinct impacts on sleep patterns.

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