Rax : developmental and daily expression patterns in the rat pineal gland and retina

Jul 14, 2011Journal of neurochemistry

Daily and developmental patterns of Rax gene activity in the rat pineal gland and retina

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Abstract

Rax expression levels in the rat peak at embryonic day 18 during retinal development.

  • Rax is a transcription factor crucial for vertebrate eye development.
  • Significant changes in Rax expression occur during retinal development.
  • In the pineal gland, Rax expression is not detectable until embryonic day 20.
  • Rax transcripts in the mature rat pineal gland increase 2-fold during the light period, peaking at dusk.
  • Rax may play a role in phenotype maintenance in the mature retina and pineal gland.

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