Relation of the International Restless Legs Syndrome Study Group rating scale with the Clinical Global Impression severity scale, the restless legs syndrome 6-item questionnaire, and the restless legs syndrome-quality of life questionnaire

A total of 458 patients showed substantial correlations between the International Restless Legs Syndrome Study Group rating scale (IRLS) and other assessment scales.

• A trend was observed where increasing scores on the CGI-1, RLS-6, and RLS-QoL scales corresponded to higher IRLS severity categories.
• Pearson correlation coefficients indicated significant relationships between IRLS scores and the comparator scales at both baseline and at the end of maintenance.
• Changes in IRLS scores from baseline to the end of maintenance also correlated with changes in scores on the comparator scales.
• The data suggest that the IRLS is a clinically meaningful tool for assessing restless legs syndrome severity.

AI simplified