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Rev‐erbα gene expression in the mouse brain with special emphasis on its circadian profiles in the suprachiasmatic nucleus
Daily patterns of Rev-erb alpha gene activity in the mouse brain, focusing on the brain’s internal clock region
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Abstract
Rev-erbalpha mRNA is most highly expressed in the suprachiasmatic nucleus (SCN) of the mouse brain.
- Positive signals of Rev-erbalpha mRNA were detected widely throughout the mouse brain.
- In the SCN, Rev-erbalpha mRNA expression peaked at early daytime (CT4) and was lowest at early night time (CT16).
- Circadian expression profiles of Rev-erbalpha mRNA remained unchanged under constant dark conditions.
- Exposure to different light-dark conditions did not affect the expression patterns of Rev-erbalpha.
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