Journal of psychopharmacology (Oxford, England)Sep 3, 2026

Safety and body processing of intravenous deuterated N,N-dimethyltryptamine (CYB004) in healthy volunteers

Psychedelic Science Weekly Brief ↗PubMed ↗DOI ↗

Updated Sep 4, 2026

Abstract

Serotonergic psychedelics like N,N-dimethyltryptamine (DMT) may have therapeutic potential in psychiatric disorders.

DMT shows pharmacokinetic variability, meaning its effects can differ significantly between individuals.
The drug has a short half-life, indicating that its effects may be brief.
Further exploration of DMT's therapeutic applications could be limited by its pharmacokinetic properties.

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