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Sarcopenia in community-dwelling older adults is associated with the diversity and composition of the gut microbiota
Muscle loss in older adults living at home is linked to differences in gut bacteria
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Abstract
Diversities at the species level in gut microbiota were detected between older adults with sarcopenia and those without (P = 0.049).
- The abundance of Prevotella and Prevotella copri was significantly lower in individuals with sarcopenia (P = 0.021 and P = 0.018, respectively).
- Individuals with sarcopenia exhibited a higher abundance of Parabacteroides sp. compared to the control group (P = 0.010).
- Differences in microbiota composition were identified between older adults with and without sarcopenia.
- Sarcopenia was associated with the presence of Anaerotruncus and Phascolarctobacterium sp., while Prevotella sp. and Prevotella copri were absent in those with sarcopenia.
- Further research is warranted to determine if changes in gut microbiota could influence the onset or progression of sarcopenia.
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