"SARS-CoV-2 spike protein induces depressive-like behaviors by disrupting astrocytic Cx43-mediated gap junction intercellular communication."
full title
How the COVID Spike Protein May Cause Depression
✨ simplified by ai
Abstract
✨ simplified by aioriginal abstract
Long COVID is a serious health issue, and depression is one of its most challenging symptoms. Researchers think that inflammation in the brain and problems with star-shaped brain cells called astrocytes may play a role in this. However, the exact way these changes lead to depression is still not fully understood.
AI SIMPLIFIES·updated 3 days ago
"(🧪) Editing a survival switch helps T-cells last longer and fight cancer better."
Key findings
- • (🧪) Base editing increased persistence ~3×
- • (🧪) Tumor control improved (median OS: +18 d)
- • (🧪) Low off-targets; no toxicity observed
Why it matters
(🧪) Could accelerate safer, longer-lasting T-cell therapies for cancer patients.
Study type undetectedCRISPRImmunotherapy