Addictive behaviors

Semaglutide's effects and brain mechanisms in alcohol use disorder

Updated

Abstract

Emerging clinical evidence suggests semaglutide may be a novel treatment for alcohol use disorder (AUD).

  • Real-world data supports the potential effectiveness of semaglutide in treating AUD.
  • Studies included both hypothesis-generating designs and confirmatory randomized controlled trials.
  • Participant groups consisted of non-treatment-seeking individuals and patients diagnosed with AUD.
  • Several cohorts involved in the studies were enriched for comorbid obesity.

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