Diabetes, obesity & metabolism

How Starting Semaglutide in Real Life in the US Affects Early Treatment Stopping and Staying on It for One Year

Updated

Abstract

Prescription behaviors for injectable semaglutide may influence early discontinuation rates.

  • Glucagon-like peptide-1 receptor agonists (GLP-1RA) are increasingly used but little is understood about their initiation in everyday clinical settings.
  • High rates of discontinuation for semaglutide have been observed in routine care.
  • Prescribing behaviors at the start of treatment could be linked to medication persistence after one year.
  • Further investigation is needed to understand the factors contributing to discontinuation during treatment.

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