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Influence of semaglutide use on the presence of residual gastric solids on gastric ultrasound: a prospective observational study in volunteers without obesity recently started on semaglutide
Semaglutide use and leftover stomach contents seen on ultrasound in non-obese volunteers starting the drug
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Abstract
In the supine position, 70% of participants taking semaglutide had solid food present in their stomachs compared to 10% of control participants.
- In the supine position, semaglutide users had a risk ratio of 3.50 for having solid gastric contents compared to controls.
- In the lateral position, 90% of semaglutide participants showed solid contents on gastric ultrasound, with a risk ratio of 7.36.
- Two hours after drinking clear liquids, 90% of control participants were considered to have empty stomachs in the supine position, while only 30% of semaglutide participants were rated as empty.
- The findings suggest that GLP-1 receptor agonists may delay gastric emptying, impacting the presence of residual gastric contents after fasting.
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