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Effects of Semaglutide and Tirzepatide on Recurrent Weight Gain After Bariatric Surgery: A Systematic Review and Meta-analysis
Semaglutide and Tirzepatide and their links to repeated weight gain after weight-loss surgery
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Abstract
Patients experienced a total weight loss of -10.97% with semaglutide and -13.63% with tirzepatide after metabolic bariatric surgery.
- Fifteen to forty percent of patients may experience recurrent weight gain after metabolic bariatric surgery.
- Semaglutide is associated with a percentage total weight loss of -10.97%, based on data from eight retrospective studies.
- Tirzepatide is associated with a percentage total weight loss of -13.63% in the same patient population.
- Both semaglutide and tirzepatide are suggested to be effective for weight reduction in patients with recurrent weight gain after metabolic bariatric surgery.
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