Obesity surgery

Semaglutide and Tirzepatide and their links to repeated weight gain after weight-loss surgery

Updated

Abstract

Patients experienced a total weight loss of -10.97% with semaglutide and -13.63% with tirzepatide after metabolic bariatric surgery.

  • Fifteen to forty percent of patients may experience recurrent weight gain after metabolic bariatric surgery.
  • Semaglutide is associated with a percentage total weight loss of -10.97%, based on data from eight retrospective studies.
  • Tirzepatide is associated with a percentage total weight loss of -13.63% in the same patient population.
  • Both semaglutide and tirzepatide are suggested to be effective for weight reduction in patients with recurrent weight gain after metabolic bariatric surgery.

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Competing interests

Declarations. Ethical Approval: For this type of study, ethical approval is not needed. Informed Consent: For this type of study, formal consent is not needed. Competing interests: The authors declare no competing interests.
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